What is IVF Success Rate ? If one opts for IVF for the first time; the most important thing to know is the success rate of an IVF procedure. Around the world it varies from 35% to 40%. While in some developed countries like Spain; it hovers around the upper limit; it...
Before a male’s sperm can fertilize a woman’s egg, it must first attach itself to the outside of the egg’s shell. Once this is accomplished, fertilization may take place. In as little as one second after being linked, the sperm finds its way through the egg’s outer layer and into the egg’s inside (cytoplasm), where fertilization takes place.
The sperm may be unable to enter the outer layer of the egg at some point for a variety of reasons. It is possible that the egg’s outer layer is too thick or difficult to penetrate, or that the sperm is unable to swim. An intracytoplasmic sperm injection (ICSI) may be performed in conjunction with in vitro fertilization (IVF) to aid in the fertilization of the egg in certain situations. A single sperm is used in ICSI, and it is injected directly into the cytoplasm of the egg. It is estimated that ICSI fertilizes 50% to 80% of the eggs.
Everything You Need To Know About ICSI
What is ICSI?
IVF (Intracytoplasmic Fertilization and Sterilization) is a highly sophisticated reproductive method that takes place in an embryology lab during an IVF treatment and involves the injection of one sperm directly into a woman’s egg to produce one fertilized embryo. ICSI IVF is one of two types of fertilization procedures that may be utilized during IVF, the other being Conventional IVF Fertilization.
An embryologist uses ICSI to choose and use the sperm that seems to be the most compatible match for the egg, which is then directly injected into the egg. Sperm are picked based on their morphology (shape) and passage through the egg (forward movement). The sperm are then extracted from the sperm-drop and placed onto a microtool known as an ICSI needle for further processing.
The embryologist transfers the sperm from the ICSI needle to a media drop holding the eggs after it has been placed in the needle. The embryologist may carefully hold the egg in the correct injection position with the use of a micro tool known as a holding pipette. The holding pipette exerts a little suction on the egg, enabling the embryologist to precisely position the egg for injection.
When the embryologist is ready, he or she will bring the ICSI needle containing the sperm down to the other media drop and align it with the egg. It is necessary to carefully put the ICSI needle into the side of the egg underneath the polar body. When the egg is perforated, it is sucked into the needle and gently mixed with a little quantity of ooplasm before the sperm is inserted into the egg.
The sperm is introduced into the egg after the zona pellucida and oolemma have been perforated. Based on how many eggs were collected during that cycle, embryologists would often mix numerous combinations of egg and sperm to create a single embryo.
Who Needs It?
ICSI may be the best option if male factor infertility is an issue (which is normally detected by a semen study). ICSI is a procedure that efficiently removes male infertility by introducing sperm cells directly into the egg during the fertilization process. Sperm count, motility, and morphology are all important factors in male fertility, and they are all required for sperm to properly encounter and penetrate an egg during a natural conception procedure.
ICSI eliminates the uncertainty of whether a few vigorous, healthy sperm make the risky trek from the man’s epididymis to the vagina, cervix, uterus, and fallopian tubes to finally locate the egg; it ensures that they do. ICSI may also be an excellent alternative to an irreversible vasectomy or for men who are paralyzed due to a spinal cord injury.
It is not just male factor infertility that leads to the decision to use ICSI. In addition to these causes, your reproductive endocrinologist may propose ICSI for the following:
- If prior IVF rounds resulted in a low number of fertilized eggs or none at all
- It is possible to become pregnant with frozen sperm and thawed sperm if the frozen sperm is inactive
- Use frozen eggs only if you are certain you will be able to successfully fertilize them since the process of vitrification may harden the egg’s outer shell
- It is typically suggested to utilize ICSI while doing Preimplantation Genetic Testing (PGT) since the presence of extra sperm near the embryo might affect the findings
- Simply to increase the likelihood of fertilization
ICSI is a delicate procedure that should only be performed by qualified embryologists in a very contemporary and high-tech laboratory environment. One of the benefits of the ICSI procedure is that it only takes one sperm per egg and may be used on patients who are experiencing male infertility. As far as the patients are concerned, ICSI is no different from normal in vitro fertilization.
Worldwide, it’s believed that around 15% of couples who are actively trying to conceive are dealing with infertility.
In Vitro Fertilization (IVF)
In vitro fertilization (IVF) is an advanced reproductive technique that aids infertility, genetic issues, and childbirth.
In layman’s terms, azoospermia means no sperm while oligozoospermia means not many sperms.
Being parents adds joy to the lives of many couples. However, while it is easy for some to become parents, for some others, it can be complicated.
Ovulation is a crucial step in the menstrual cycle of women. The ovary releases a mature egg that reaches the uterus through fallopian tubes.
A simple treatment, known as intrauterine insemination (IUI) places healthy sperm straight into your uterus, allowing them to move closer to your egg.
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We had an excellent experience at Oyster & Pearl hospital. We were here for emergency baby delivery and after that NICU for baby. Both deliveries for the mother and NICU for the kid were so delicately taken care of that by god's grace everything went well. Dr. Amita, Dr. Nivedita, Resident doctor staff, nursing staff, administration (Akash), cashless facility (TPA) dept everyone's efforts are well appreciated! Recommended.
Best paediatric hospital in Pune. Dr Amita Phadnis is the best paediatric doctor in Pune. The entire staff is the best and supportive. Also, sister Merry is very polite and supportive. Thank you.
Best Maternity hospital around the corner for Pimple Saudagar and nearby residents. Superb management and helpful staff always available for our service. Easy admission and discharge with well experienced staff. Highly recommended!!
ONP Rahatani, is an excellent hospital in Pimple Saudagar. Went there for my delivery. Doctors are really humble and ready to resolve all doubts. Staff is very polite and cooperative. Admin support was exceptional in all matters from the date of admission to discharge. The atmosphere of hospital was fresh, clean and positive. Hospital was well organised and everyone working in the hospital treats its patients with respect and dignity. highly recommend this hospital.
ONP Leela hospital is best gynecology hospital in pimple saudagar, hospital is well organized and treats patients with dignity and respect. The staff is warm and caring. I would recommend this to all those in need of treatment.
I am very happy with the services provided by ONP hospitals best IVF and Maternity hospital. I am also thankful to all the doctors and staff members who supported us throughout the entire process. Special thanks to Dr. Avinash for guidance and encouragement.
Shraddha Kulkarni Shukla
Dr Abhijeet Wahegaonkar is a God in orthopaedics with an excellent team ! ONP had Superb management with a caring approach. From admission till discharge, fantastic service.
Took vaccine here on 7th June. Everything is well managed and the staff is also good. Enough two wheeler parking space. The whole process of vaccination took 45 mins. Thank you team.
It is the best IVF hospital in Pune. All the staff are very polite. Food quality is very good. Feeling happy and satisfied. Good service. Thank you so much to every doctor and every nurse.
The services and hospitality are appreciated. The nurses were available on call and very cooperative.Overall satisfied with the food quality, environment and services. Thank you.
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